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UpGene specifications

Information


Unique identifier OMICS_08713
Name UpGene
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability No
Maintained No

Maintainer


This tool is not available anymore.

Publication for UpGene

UpGene in publications

 (3)
PMCID: 4186344
PMID: 25340050
DOI: 10.3389/fbioe.2014.00041

[…] a number of additional software applications have been created to aid gene redesign and customization for synthesis. few of these tools were unattainable at the time of this study. these include upgene (gao et al., ), gene morphing system (gems) (jayaraj et al., ), and gene composer (lorimer et al., ). the basic functionality of these programs can be largely found in other currently […]

PMCID: 2954917
PMID: 20854688
DOI: 10.1186/1742-4690-7-75

[…] and morphology should help to enhance our global understanding of the basis of htlv-1 particle infectivity, transmission and pathogenesis., a codon-optimized htlv-1 gag gene was designed using the upgene program [] and synthesized by genscript co. (piscataway, nj). the synthetic htlv-1 gag contains an optimal kozak consensus sequence [,] at the 5' end of the gene: gccaccatgg (start codon […]

PMCID: 2864737
PMID: 20463955
DOI: 10.1371/journal.pone.0010492

[…] (ad5)-based vectors encoding the wildtype (adha.wt) or a codon-optimized (adha.cod) hemagglutinin (ha) gene from a/california/04/2009 (h1n1)pdm influenza virus. codon-optimization using the upgene algorithm improves expression levels of the antigen in infected mammalian cells and consequently enhances immune responses against the antigen in vivo. the generation of the recombinant […]


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UpGene institution(s)
Department of Molecular Genetics and Biochemistry and Department of Surgery, University of Pittsburgh, Pittsburgh, PA, USA

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