UROBORUS

[…] et al., ). here, this analysis is extended by 6 additional algorithms: acsf (you et al., ), circexplorer2 (zhang et al., ), ciri2 (gao et al., ), dcc (cheng et al., ), knife (szabo et al., ), and uroborus (song et al., ) (see table ). overall, the sensitivity and specificity of predicted circrnas are compared by assessing the quantities of circrnas found by each algorithm as well […]

[…] circrnas from rna-seq data. notable circrna identification tools are find_circ [], mapsplice2 [], segemehl [], circexplorer [], circrna_finder [], ciri [], acfs [], knife [], nclscan [], dcc [] and uroborus []. information regarding these tools is listed in . in addition, circview, a platform visualization tool, is specifically developed to visualize circrnas detected from these tools []. […]

[…] the other two software systems generate putative circrna sequences post-alignment with the genome or transcriptome [,,]. , circrna_finder, circexplorer, dcc, mapsplice, segemehl, find-circ, and uroborus detect circrna sequences based on the second approach for identification of circrna sequences which is the fragmented-base or segmented read approach. in this approach, the software detects […]

[…] demand of comprehensive detection of circrnas, several different pipelines with better performance in circrna analysis have been developed, including find_circ, ciri, circrnafinder, circexplorer, uroborus, etc., for further study of circrnas. however, most of existing work on circrna is based on bulk sequencing, in which individual cell properties and heterogeneities are hidden. furthermore, […]

[…] or rt-pcr artifacts. until recent years, due to the high throughput sequencing technologies coupled with exonuclease-based enrichment strategies and new bioinformatic tools, such as ciri, knife and uroborus, the identification, biogenesis and function of circrnas were widely reported in animals, such as human, mouse and drosophila –., in humans, circularized exons are typically bracketed […]