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variable Nearest Neighbor v-NN

Predicts chemical-induced genome-wide changes in gene expression. V-NN uses information from qualified near neighbors to make predictions. It takes advantage of up-to-date experimental data, as soon as they are made available and incorporated into the dataset used by the method, without the need to re-train any model. This tool can be used for modeling large-scale, genome-wide, chemical-induced changes gene expression changes.

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v-NN classification

v-NN specifications

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v-NN distribution


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v-NN support


  • Ruifeng Liu <>
  • Anders Wallqvist <>
  • Mohamed AbdulHameed <>


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Department of Defense Biotechnology High Performance Computing Software Applications Institute, Telemedicine and Advanced Technology Research Center, U.S. Army Medical Research and Materiel Command, Fort Detrick, MD, USA

Funding source(s)

Supported by the U.S. Army Medical Research and Materiel Command (Ft. Detrick, MD) as part of the U.S. Army’s Network Science Initiative, and by the Defense Threat Reduction Agency (Grant No. CBCall14-CBS-05-2-0007).

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