Facilitates access to existing information on T-cell receptor (TCR) antigen specificities. VDJdb is a comprehensive database of antigen-specific TCR sequences acquired by manual processing of published studies that report the ligand specificities of defined T-cell clonotypes. This database features more than 5000 records of mouse, monkey and human TCR sequences aggregated from more than 100 published studies.
Pirogov Russian National Research Medical University, Moscow, Russia; Center for Data-Intensive Biomedicine and Biotechnology, Skolkovo Institute of Science and Technology, Moscow, Russia; Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Moscow, Russia; Central European Institute of Technology, Brno, Czech Republic; Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia; Theoretical Biology and Bioinformatics, Science Faculty, Utrecht University, Utrecht, Netherlands; Department of Immunology, St. Jude’s Children’s Research Hospital, Memphis, TN, USA; Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff, UK; Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, VIC, Australia; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA; Viral Immunology Systems Program, Kirby Institute, School of Medical Sciences, University of New South Wales, Kensington, NSW, Australia; Center for Immunology of Infectious Diseases and Vaccines, National Institute for Public Health and the Environment, Bilthoven, Netherlands; Systems Immunity Research Institute, Cardiff University School of Medicine, Cardiff, UK
VDJdb funding source(s)
Supported by Pirogov Russian National Research Medical University; European Union’s Horizon 2020 Research and Innovation Programme ; Ministry of Education, Youth and Sports of the Czech Republic under the project CEITEC 2020 [LQ1601]; Wellcome Trust Senior Investigator Awards; Cancer Research Wales PhD Studentship.