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Veridical specifications
Information
| Unique identifier | OMICS_02630 |
|---|---|
| Name | Veridical |
| Software type | Package/Module |
| Interface | Command line interface |
| Restrictions to use | License purchase required |
| Operating system | Unix/Linux, Mac OS |
| Programming languages | C++ |
| License | Commercial |
| Computer skills | Advanced |
| Maintained | Yes |
Versioning
No version available
Maintainers
- person_outline Veridical Team
- person_outline Peter Rogan
Additional information
Publication for Veridical
Validation of predicted mRNA splicing mutations using high-throughput transcriptome data.
Veridical citations
(3)In silico prediction of splice altering single nucleotide variants in the human genome
[…] o recruit variants that do not cause any alternative splicing. Several attempts have been made to integrate RNA-seq data into in silico tools in order to improve predictions (e.g. SpliceFinder () and Veridical ()). Although their reliability and ease of use require further evaluation, integration of multi-information into one single tool has become a trend.Our dataset was limited to SNVs because t […]
Interpretation of mRNA splicing mutations in genetic disease: review of the literature and guidelines for information theoretical analysis
[…] eo-Johnson transformation of the expressed read count distribution, parametric statistics are used to compare normal and abnormal mRNA species (exon skipping, intron inclusion, and cryptic site use). Veridical is designed to be used with large data sets, as the statistical analysis gains power with increasing numbers of control samples. A recent study of 442 breast cancer tumors from the Cancer Ge […]
Splicing mutation analysis reveals previously unrecognized pathways in lymph node invasive breast cancer
[…] d bmr calc-covg. All FDRs that we report pertaining to the MuSiC analysis used the Fisher's combined P-value (FCPT), convolution (CT) and likelihood ratio (LRT) statistical tests.The software program Veridical was used for in silico validation of all predicted splicing mutations using its default settings. At the time the program was run, Veridical rounded p-values to 2 decimal places. Validated r […]
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