Veridical statistics

Tool stats & trends

Looking to identify usage trends or leading experts?

Veridical specifications

Desktop

Information

Unique identifier	OMICS_02630
Name	Veridical
Software type	Package/Module
Interface	Command line interface
Restrictions to use	License purchase required
Operating system	Unix/Linux, Mac OS
Programming languages	C++
License	Commercial
Computer skills	Advanced
Maintained	Yes

Versioning

No version available

Maintainers

Veridical Team
Peter Rogan

Additional information

This tool is integrated into the MutationForecaster software.

Publication for Veridical

Validation of predicted mRNA splicing mutations using high-throughput transcriptome data

2014 F1000Res

PMCID: 3983938

PMID: 24741438

DOI: 10.12688/f1000research.3-8.v2

Veridical citations

(3)

In silico prediction of splice altering single nucleotide variants in the human genome

2014

Nucleic Acids Res

PMCID: 4267638

PMID: 25416802

DOI: 10.1093/nar/gku1206

[…] o recruit variants that do not cause any alternative splicing. Several attempts have been made to integrate RNA-seq data into in silico tools in order to improve predictions (e.g. SpliceFinder () and Veridical ()). Although their reliability and ease of use require further evaluation, integration of multi-information into one single tool has become a trend.Our dataset was limited to SNVs because t […]

Interpretation of mRNA splicing mutations in genetic disease: review of the literature and guidelines for information theoretical analysis

2014

F1000Res

PMCID: 4329672

PMID: 25717368

DOI: 10.5256/f1000research.6038.r6917

[…] eo-Johnson transformation of the expressed read count distribution, parametric statistics are used to compare normal and abnormal mRNA species (exon skipping, intron inclusion, and cryptic site use). Veridical is designed to be used with large data sets, as the statistical analysis gains power with increasing numbers of control samples. A recent study of 442 breast cancer tumors from the Cancer Ge […]

Splicing mutation analysis reveals previously unrecognized pathways in lymph node invasive breast cancer

2014

Sci Rep

PMCID: 4231324

PMID: 25394353

DOI: 10.1038/srep07063

[…] d bmr calc-covg. All FDRs that we report pertaining to the MuSiC analysis used the Fisher's combined P-value (FCPT), convolution (CT) and likelihood ratio (LRT) statistical tests.The software program Veridical was used for in silico validation of all predicted splicing mutations using its default settings. At the time the program was run, Veridical rounded p-values to 2 decimal places. Validated r […]

Citations

Looking to check out a full list of citations?

Veridical institution(s)

Department of Computer Science, University of Western Ontario, London, ON, Canada; Department of Biochemistry, University of Western Ontario, London, ON, Canada; Cytognomix, Inc., London, ON, Canada

Veridical funding source(s)

Supported by the Canadian Breast Cancer Foundation, Canadian Foundation for Innovation, Canada Research Chairs Secretariat and the Natural Sciences and Engineering Research Council of Canada (NSERC Discovery Grant 371758-2009); by fellowships from the Ontario Graduate Scholarship Program, the Pamela Greenaway-Kohlmeier Translational Breast Cancer Research Unit, the CIHR Strategic Training Program in Cancer Research and Technology Transfer, and the University of Western Ontario.

Veridical reviews

Be the first to review Veridical