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Associated diseases

Associated diseases

ViaComplex specifications


Unique identifier OMICS_24371
Name ViaComplex
Software type Application/Script
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages Fortran
Computer skills Advanced
Version 1.0
Stability Stable
Source code URL
Maintained Yes



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  • person_outline Mauro Castro <>
  • person_outline Rita de Almeida <>

Publication for ViaComplex

ViaComplex in publications

PMCID: 5061082
PMID: 27292261
DOI: 10.1038/onc.2016.184

[…] hypoxic response (hyr) network was designed in string ( containing the selected pathways ()., gene set enrichment analysis (v2.1) was used to evaluate pathway enrichment (). viacomplex (v1.0) was used to generate representative landscape images of these results ( and )., publicly available mcf-7 chip-seq data (geo dataset gse55923) was analysed using macs2. sequence […]

PMCID: 4839732
PMID: 27100653
DOI: 10.1371/journal.pone.0153970

[…] handled by medusa software []. nodes colors include information on mms-induced changes in gene expression (microarray) and gene survival role in rnai screening. interactomes were further analyzed by viacomplex software [], which plots the gene expression (means of each replicates per gene) value over the network/interactome, and distributes the microarray signal through network objects (nodes […]

PMCID: 4548187
PMID: 26302899
DOI: 10.1038/srep13351

[…] expression responses to inducers, the obtained m(ifnγ + lps, tnfα) and m(il-4, il-13) gene networks were subsequently plotted as representative topological responses using landscape analysis with viacomplex® software. x and y-axis represent gene signature networks and the z-axis indicates an illustrative expression response to ifnγ + lps or il-4 inducers ()., to experimentally validate […]

PMCID: 3674721
PMID: 23766861
DOI: 10.1155/2013/791795

[…] information table s4). finally, to visualize the topological network properties of each node within medri network model, numeric values were projected in a 2d color representation by utilizing viacomplex software ( []., the protein content of each sample was measured by lowry method []., results were expressed as the mean ± sem of three […]

PMCID: 3639264
PMID: 23637898
DOI: 10.1371/journal.pone.0061743

[…] was used and a mean value of expression for each gene was generated for both groups “a” and “b”. the mean value of expression was then overlaid in cpi-ppi-derived subnetworks with the software viacomplex 1.0 . by providing gene expression data and interactomic networks, the software viacomplex generates a landscape view of gene expression in a specific network., to predict the solubility […]

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ViaComplex institution(s)
Unidade de Bioinformática, Departamento de Bioquimica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Instituto de Fisica, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Nucleo de Bioinformatica, Departamento de Genética, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Departamento de Fisica, Universidade Federal de Santa Maria, Santa Maria, Brazil
ViaComplex funding source(s)
Supported by the Brazilian Agencies FAPERGS, CAPES and CNPq.

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