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Virus-VG specifications


Unique identifier OMICS_28163
Name Virus-VG
Software type Application/Script
Interface Command line interface
Restrictions to use None
Input data A data set of next-generation sequencing reads and a set of contigs assembled from these.
Operating system Unix/Linux
Programming languages Python
License MIT License
Computer skills Advanced
Version 0.0.1
Stability Stable
Maintained Yes




No version available


  • person_outline Alexander Schonhuth
  • person_outline Jasmijn Baaijens

Publication for Virus-VG

Virus-VG citations


Oncolytic efficacy of thymidine kinase deleted vaccinia virus strain Guang9

PMCID: 5522336
PMID: 28465492
DOI: 10.18632/oncotarget.17125
call_split See protocol

[…] The vaccinia virus VG9 strain was obtained from National Institutes for Food and Drug Control (NIFDC, Beijing 100050, China). The vaccinia virus Western Reserve strain (WR) was kindly provided by Professor Liu (In […]


Host Pathogen Coevolution and the Emergence of Broadly Neutralizing Antibodies in Chronic Infections

PLoS Genet
PMCID: 4956326
PMID: 27442127
DOI: 10.1371/journal.pgen.1006171

[…] at determines selection on both immune and viral populations. We model the binding affinity as a weighted dot product over all loci, which for antibody Aα chosen from the genotype space α∈1…2ℓ+ℓ^ and virus Vγ with γ ∈ 1 … 2ℓ has binding affinity EtotC(Aα,Vγ)=∑i=1ℓκiCAiαViγ︸variable viral region+∑i=ℓ+1ℓ+ℓ^κ^iCAiα︸conserved viral region≡Eα γC+E^αC(1) where, Aiα=±1 denotes the ith locus of the α anti […]


Comparison on Virulence and Immunogenicity of Two Recombinant Vaccinia Vaccines, Tian Tan and Guang9 Strains, Expressing the HIV 1 Envelope Gene

PLoS One
PMCID: 3491055
PMID: 23139778
DOI: 10.1371/journal.pone.0048343

[…] ecombinant vaccinia viruses are highly attenuated in vivo compared to their parent virus. Moreover, we also validated the fact VG9-E virulence is weaker than that for VTT-E. We supposed that vaccinia virus VG9 is safer than its parent strain, VTT, not only as a vaccinia virus vector for HIVs, but also may as a vector for gene therapy of tumors.After two inoculations with pDRVISV1.0-env, and one bo […]


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Virus-VG institution(s)
Centrum Wiskunde & Informatica, Amsterdam, Netherlands; University Medical Center Utrecht, Utrecht, Netherlands; University of Duisberg-Essen, Essen, Germany; Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Vrije Universiteit, Amsterdam, Netherlands; Utrecht University, Utrecht, Netherlands

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