A publicly available web resource that streamlines and simplifies the process of gleaning insight from protein structures. In contrast to most molecular graphics tools, the user interface of Aquaria is organized primarily by protein sequence, not structure. A user starts by specifying a protein of interest by name and organism, by identifier or by URL; Aquaria then generates a concise visual summary of all related PDB structures, using a precalculated all-against-all comparison of Swiss-Prot and PDB sequences (updated monthly). Aquaria is designed for biologists; its user interface creates clear and useful default views that show only the most relevant structural information tightly integrated with sequence, features and text that provide biological context.
