A user-friendly tool for analyzing and visualizing IG and TR repertoires based on NGS data. IMEX offers several algorithms for analyzing the clonality and diversity on multiple levels such as V-(D)-J arrangement, CDR, and nucleotide sequences of the whole reads. Moreover, it also provides features for analyzing primer efficiency. IMEX includes various visualization possibilities such as pie charts, histograms, line charts, bubble charts, and heat maps.
Provides immunology researchers with powerful data analysis infrastructure. VDJserver offers tools for performing immune repertoire analysis with a focus on collaboration, streamlined metadata capture, and reproducibility. It also allow to get basic repertoire characterization results for both B cell receptor and T cell receptor repertoires.
Offers a platform for comprehensive analyses of B cell receptor repertoires, using IMGT/HighV-QUEST formatted data. bcRep is a R package that combines techniques for studying clones and also the total set of input sequences or subsets of sequences. This program allows users to filter these sequences for their functionality or junction frame usage, and clones also for their size.
A web-based, interactive application for the analysis of immunoglobulins and T cell receptors using next-generation sequencing data. ARResT/Interrogate can organize and filter large amounts of immunogenetic data by various criteria. It calculates several relevant statistics, and presents results in the form of multiple interconnected visualizations. ARResT/Interrogate is implemented primarily in R, and is freely available.
A web-based graphical user interface application that allows browsing and analyzing immune repertoire sequencing (RepSeq) data. VDJviz can be used to visualize results of MITCR, MIGEC, MIXCR and MIGMAP RepSeq processing software as well as popular IMGT/HighV-QUEST and ImmunoSEQ Analyzer services. VDJviz can be installed and used as a local server. Alternatively you can use an online demo version which currently has an upload limit of 25 datasets each having size at most 10000 clonotypes.
Aims to manipulate, analyze and visualize antibody repertoire sequence data. BRepertoire is a web application that can be used for T cell and non-human sequencing data. This tool supports the calculation of a set of statistical significance and effect size measures. The calculation and analysis of physico-chemical properties provides a representation of amino acid sequences.
Contributes self-developed plots for the descriptive comparative investigation of immune repertoires. ClonoPlot allows the visualization of observations in comparative B cell receptors (BCR) and T cell receptors (TCR) repertoire analysis. It removes any requirement for users to become familiar with the programming language R in order to create high-quality figures. The tool can be adapted by user to the latest developments in the field or incorporate additional features based on their existing in-house expertise.