VLAD statistics

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Citations per year

Number of citations per year for the bioinformatics software tool VLAD

Tool usage distribution map

This map represents all the scientific publications referring to VLAD per scientific context
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Associated diseases


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VLAD specifications


Unique identifier OMICS_21883
Alternative name Visual annotation display
Interface Web user interface
Restrictions to use None
Input data A set of objects and optionally a customized data set of Gene Ontology, a personal ontology.
Input format GO,OBO
Output data A graphical and tabular representations of the ontology terms associated with the user-supplied gene list (i.e., the query set) and the calculated significance scores.
Output format HTML,XLS,TSV
Computer skills Basic
Version 1.6.0
Stability Stable
Maintained Yes


No version available


  • person_outline Carol J. Bult
  • person_outline Joel Richardson

Publication for Visual annotation display

VLAD citations


A retinoic acid dependent stroma leukemia crosstalk promotes chronic lymphocytic leukemia progression

Nat Commun
PMCID: 5934403
PMID: 29725010
DOI: 10.1038/s41467-018-04150-7

[…] using the “weighted trimmed mean of M-values” described elsewhere. After normalization, differential gene expression was performed using the limi package in R. Annotation analysis was performed using VLAD – Visual Annotation Tool at MGI (Mouse Genome Informatics). No statistical method for sample size choice was used; however, a similar number of mice is generally used in the field for similar exp […]


Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome

Nat Commun
PMCID: 5923383
PMID: 29703891
DOI: 10.1038/s41467-018-03770-3
call_split See protocol

[…] ower than 0.1. In edgeR differential expression analysis, we selected genes up or down regulated with a p-value less than 0.05. Gene ontology analysis was performed using the mouse genome informatics visual annotation display. For the analysis of the biological term fold enrichment, a ratio between the frequency of genes in our set to frequency of genes in the whole genome was calculated. […]


Improving Interpretation of Cardiac Phenotypes and Enhancing Discovery With Expanded Knowledge in the Gene Ontology

Circ Cardiovasc Genet
PMCID: 5821137
PMID: 29440116
DOI: 10.1161/CIRCGEN.117.001813

[…] s freely available functional analysis tools, including Database for Annotation, Visualization and Integrated Discovery, g:profiler, Protein Analysis Through Evolutionary Relationships (PANTHER), and Visual Annotation Display (VLAD). Full methods are available in the Data Supplement. […]


Evolutionary adaptation revealed by comparative genome analysis of woolly mammoths and elephants

PMCID: 5737375
PMID: 28369217
DOI: 10.1093/dnares/dsx007

[…] d amino acid substitutions was analysed using PANTHER (http://pantherdb.org/ (9 February 2017, date last accessed)), WebGestalt (http://www.webgestalt.org/ (9 February 2017, date last accessed)), and Vlad (http://proto.informatics.jax.org/prototypes/vlad/ (9 February 2017, date last accessed)), respectively. Using a set of SNVs (four variant-supporting reads, mapping quality ≥20, allele frequency  […]


Type IV collagen drives alveolar epithelial–endothelial association and the morphogenetic movements of septation

BMC Biol
PMCID: 4942891
PMID: 27412481
DOI: 10.1186/s12915-016-0281-2

[…] homologous and named by Ensembl with BioMart (http://useast.ensembl.org/index.html). Once the murine homologous gene list was generated, functional classification of genes was performed using MGI and Vlad (http://proto.informatics.jax.org/prototypes/vlad/). […]


Precise genetic mapping and integrative bioinformatics in Diversity Outbred mice reveals Hydin as a novel pain gene

Mamm Genome
PMCID: 4032469
PMID: 24700285
DOI: 10.1007/s00335-014-9508-0

[…] . The functional relationship networks generated by MouseMap and IPA were assessed for enrichment of Gene Ontology (GO) (Ashburner et al. ) and Mammalian Phenotype (MP) (Smith and Eppig ) terms using VLAD (http://proto.informatics.jax.org/prototypes/vlad-1.0.3/), a web-based tool for statistical term enrichment (annotation date: November 2, 2011).For each candidate gene, gene expression annotation […]

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VLAD institution(s)
Mouse Genome Informatics (MGI) Database Consortium, The Jackson Laboratory, Bar Harbor, ME, USA
VLAD funding source(s)
Supported, in part, by NIH HG00330-P1

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