Volarea statistics

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Citations per year

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Associated diseases

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Volarea specifications


Unique identifier OMICS_08148
Name Volarea
Software type Package/Module
Interface Graphical user interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Computer skills Medium
Stability Stable
Maintained Yes


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  • person_outline Maria J. Ramos <>

Publication for Volarea

Volarea in publications

PMCID: 5034317
PMID: 27658476
DOI: 10.1038/srep33776

[…] cγ of y33 (extracellular end of tm1) and y256 (extracellular end of tm7), compared to the initial state (post-equilibration), and (ii) the water occupancy in the periplasmic cavity measured using volarea (). this double criteria approach allowed us to discriminate between replicas simply increasing its inner cavity pore radius compared to replicas opening towards the periplasmic side. […]

PMCID: 4757871
PMID: 26887338
DOI: 10.1038/srep21763

[…] studies can profile the dimerization and allosteric regulation mechanism of mglu1. as shown in , the occupied surface areas of ligand fitm and six cholesterol molecules on mglu1 are calculated by volarea. the cholesterol molecules occupy an area about 450 å2 in dimer a or b during the molecular dynamics simulations. it indicates that the cholesterol molecules can interact with dimer a and b. […]

PMCID: 4266597
PMID: 25482395
DOI: 10.1038/ncomms6635

[…] between acceptor and hydrogen should be <3.5 å; second, the angle between hydrogen-donor-acceptor should be <30°. surface contact areas of interacting residues were calculated employing volarea implemented in vmd. the area is calculated using a probe radius defined as an in silico rolling spherical probe that is screened around the area of doc exposed to coh and also coh area […]

PMCID: 3901456
PMID: 24555108
DOI: 10.5256/f1000research.2772.r2228

[…] to examine the ribonucleolytic activity. the nuclear translocation activity of the submitted ang mutant is examined by calculating the sasa of nuclear localization signal residues 31rrr 33 using volarea ( http://www2.fc.up.pt/portobiocomp/software/volarea/home.html), a vmd plug-in., step 4: data output. the output panel shows whether the user-submitted ang mutation exhibited conformational […]

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Volarea institution(s)
REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto, Porto, Portugal

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