WebGestalt specifications


Unique identifier OMICS_02222
Name WebGestalt
Alternative name WEB-based GEne SeT AnaLysis Toolkit
Interface Web user interface
Restrictions to use None
Input data Some values for individual genes.
Output data The analysis summary, gene identifier (ID) mapping information, GO Slim summary and enrichment results.
Computer skills Basic
Stability Stable
Maintained Yes


WebGestalt articles

WebGestalt citations

PMCID: 5622528

[…] binomial test. p values were adjusted using the benjamini-hochberg method., the list of genes with significantly altered expression (benjamini-hochberg adjusted p < 0.05) was analyzed using webgestalt [38]. of the 2080 gene ids uploaded to the program, 1611 mapped to unique entrez gene ids and were used in the analysis while 464 could not be mapped and were excluded. the reference set […]

PMCID: 5739609

[…] genes between oscc specimens obtained from lymph node positive versus lymph node negative patients. selection criteria were p < 0.05 (based on anova test) and a fold-change barrier of ±2., webgestalt and genecodis3 agreed on the enrichment of a myocyte enhancer factor recognition site, recurrent in five genes of our dataset (adjusted p-value = 0.0007): the hmef2_q6 binding site. four […]

PMCID: 5438707

[…] package. we observed two major clusters, but these clusters are not as sharply distinguishable as dna methylation clusters (supplementary figure 8). we also did enrichment analysis of degs using webgestalt and ipa. we observed enrichment of hematopoietic cell lineage, cytokine-cytokine receptor interaction, b cell receptor signaling pathway, natural killer cell mediated cytotoxicity, […]

PMCID: 4866393

[…] significant when fdr < 0.05 and the difference between observed and expected genes was larger than one. enrichment analyses based on an alternative (hypergeometric) test were carried out using webgestalt [27]., transcription factor binding site enrichment analysis was carried out using the transcription factor target analysis toolkit from webgestalt [27]., to represent the distribution […]

PMCID: 4673270

[…] expressed genes to infer pathways and regulatory mechanisms associated with cox-1 expression was performed by webgestalt (web-based gene set analysis toolkit; http://bioinfo.vanderbilt.edu/webgestalt/) [73]. enrichment p-values were generated by the fisher's exact test and adjusted by benjamini and hochberg's multiple-test [72]. raw and processed rna-seq data files are available […]

WebGestalt institution(s)
Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA
WebGestalt funding source(s)
Supported by National Cancer Institute (NCI) [U24 CA210954]; Leidos Biomedical Research, Inc. [15X038]; Cancer Prevention & Research Institutes of Texas Scholarship (CPRIT) [RR160027] and McNair Medical Institute Scholarship.

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