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Webserver fOr Position Related data analysis of gene Expression in Prokaryotes WoPPER


Integrates transcriptional expression data and genomic annotations to identify groups of physically contiguous genes characterized by regional differential expression in bacterial genomes. WoPPER Is a web app that can analyze any RNA-seq or microarray-based gene expression dataset from any microorganism with a sequenced and annotated genome. This resource provides researchers with novel and informative insights regarding the correlation between gene expression and chromosomal organization in bacterial genomes.

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WoPPER classification

WoPPER specifications

Web user interface
Input data:
Requires as input at least one Gene Expression Data file (GED file) containing the genome-wide differential expression levels.
Output data:
Provides three types of output: Tabular Results, Circular Plots and Linear Plots.
Computer skills:
Restrictions to use:
Input format:
Programming languages:

WoPPER support


Additional information


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Institute of Biomedical Technologies, National Research Council, Segrate, Milan, Italy; Institute of Biomedical Technologies, National Research Council, Bari, Italy; Department of Life Sciences, Center for Genome Research, University of Modena and Reggio Emilia, Modena, Italy; IFOM, the FIRC Institute of Molecular Oncology, Milan, Italy; Institute of Molecular Genetics, National Research Council, Pavia, Italy

Funding source(s)

This work was supported by the Italian Ministry of Education and University, PRIN Project [2010P3S8BR 002]; National Research Council (CNR) Flagship Project InterOmics; AIRC Start-up grant 2015 [N.16841].

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