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WEGO specifications


Unique identifier OMICS_04145
Alternative name Web Gene Ontology Annotation Plot
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Jun Wang <>
  • person_outline Lars Bolund <>

Publications for Web Gene Ontology Annotation Plot

WEGO in pipelines

PMCID: 5764247
PMID: 29324867
DOI: 10.1371/journal.pone.0190096

[…] database and the 'go term finder' (http://www.yeastgenome.org/help/analyze/go-term-finder). after obtaining the go annotations for the degs, the go functional classification was executed with wego[]. genes usually participate in certain biological functions by interacting with each other. to assign the degs to specific biological pathways, kyoto encyclopedia of genes and genomes (kegg) […]

PMCID: 5784662
PMID: 29368590
DOI: 10.1186/s12870-017-1220-2

[…] a relatively large minimum module size of 30 and a medium sensitivity (deepsplit = 2) to cluster splitting []. the resulting genes (threshold weight ≥ 0.1) involved in psarfs was analyzed with bgi wego (http://wego.genomics.org.cn/) to assign gene ontology (go) terms []. cytoscape was implemented for visualizing interaction networks []., the recent development of the rna-seq method provides […]

PMCID: 5818499
PMID: 29459688
DOI: 10.1038/s41598-018-21580-x

[…] 95% confidence interval for protein identification., the heat map was generated using heatmap v2.0 (r-package). gene ontology enrichment analysis of different abundant proteins was implemented by wego software (http://wego.genomics.org.cn/cgi-bin/wego/index.pl), in which gene length bias was corrected. false discovery corrected p value < 0.05 was chosen to include as much as possible […]

PMCID: 5818499
PMID: 29459688
DOI: 10.1038/s41598-018-21580-x

[…] annotated with go terms as well as interpro and pfam domains they contain. go annotation and enrichment analysis of all 431 different abundant proteins was implemented by the kobas software and wego software, respectively, in which gene length bias was corrected. in this study, 431 differential expression genes involve 206 pathways (table ). figure  shows the results of pathways enrichment, […]

PMCID: 5827294
PMID: 29520289
DOI: 10.3389/fpls.2018.00217

[…] gene expression profiling, gene ontology (go) enrichment analysis of functional significance was applied using the hypergeometric test to map all differentially expressed genes to terms in the bgi wego (web gene ontology annotation plotting, http://wego.genomics.org.cn/) looking for significantly enriched go terms in the differentially expressed genes, and comparing them to the transcriptome […]

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WEGO in publications

PMCID: 5923184
PMID: 29704894
DOI: 10.1186/s12917-018-1468-2

[…] enrichment analysis of the target genes was performed using goseq [] to detect the significantly enriched go terms of the host target. the go terms with p < 0.05 were considered significant. the wego software (http://wego.genomics.org.cn) was used to produce histograms of the go annotations, including three fields: cellular component, biological process and molecular function., the stem-loop […]

PMCID: 5919661
PMID: 29698526
DOI: 10.1371/journal.pone.0196537

[…] (2010) r package. the p-value was adjusted using the q-value []. the following threshold was applied to identify differentially expressed genes: q-value < 0.005 and |log2 (fold change)| ≥ 1. the wego online program (http://wego.genomics.org.cn/cgi-bin/wego/index.pl) was used for the go functional classification of all unigenes and determination of the distribution of gene functions., total […]

PMCID: 5918905
PMID: 29695227
DOI: 10.1186/s12864-018-4702-1

[…] databases including national center for biotechnology information (ncbi) nr, swissprot, kyoto encyclopedia of genes and genomes (kegg), and clusters of orthologous groups (cog). blast2go [] and wego [] were used for gene ontology (go) analysis with default settings., we mixed the unigene data obtained from the transcriptomes of the two c. indicum germplasms to form a pan-transcriptome. […]

PMCID: 5908857
PMID: 29674749
DOI: 10.1038/s41598-018-24477-x

[…] sequences were assigned to go enrichment and kegg pathway to obtain a clear biological information map of the mirnas-dependent key biological processes. web gene ontology annotation plotting (http://wego.genomics.org.cn/cgi-bin/wego/index.pl) were performed to analyze the mirna target genes classification based on their associated cellular component, molecular function and biological process., […]

PMCID: 5908868
PMID: 29674689
DOI: 10.1038/s41598-018-24727-y

[…] fold change in expression| ≥ 1 and p-value ≤ 0.05 were defined as degs., for functional analysis of degs, the degs were classified according to go terms using the panther classification system and wego, and they were annotated into kegg pathways using the capitalbio molecule annotation system (mas 3.0, http://bioinfo.capitalbio.com/mas3/)., the target genes of selected mirnas were predicted […]

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WEGO institution(s)
BGI-Shenzhen, Shenzhen, Guangdong, , China; University of Auckland, Auckland, New Zealand; Zhejiang Hospital, Hangzhou, Zhejiang, China; Lars Bolund Institute of Regenerative Medicine, BGI-Qingdao, Qingdao, China; Institute of Biomedicine, Aarhus University, Aarhus, Denmark; Department of Oncology, Fujian Medical University Union Hospital, Fuzhou, China; Fujian Key Laboratory of Translational Cancer Medicine, Fuzhou, China; Department of Stem Cell Research Institute, Fujian Medical University Stem Cell Research Institute, Fuzhou, China; Department of Biology, University of Copenhagen, Copenhagen, Denmark
WEGO funding source(s)
Supported by the Collaborative Innovation Center of High Performance Computing; Critical Patented Project of the Science and Technology Bureau of Fujian Province, China [2013YZ0002–2]; Zhejiang Province for Public Welfare [2016C33122]; Joint Project of the Natural Science and Health Foundation of Fujian Province, China [2015J01397].

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