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What’s The Function of these genes? WTFgenes

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Interprets experimentally-identified lists of genes. WTFgenes uses hypergeometric and model-based approaches. It permits to know what is the function of different genes thanks to Bayesian Term Enrichment Analysis (TEA). The tool can readily be extended to allow for datasets that are structured temporally, spatially, or by genomic region; to use domain-specific biological knowledge; or to incorporate additional lines of evidence such as quantitative data.

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WTFgenes classification

WTFgenes specifications

Software type:
Package/Module
Restrictions to use:
None
Programming languages:
C++, Javascript
Stability:
Stable
Maintained:
Yes
Interface:
Command line interface
Operating system:
Unix/Linux
Computer skills:
Advanced
Requirements:
Node, clang, gsl, boost

WTFgenes distribution

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WTFgenes forum

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No open topic.

WTFgenes classification

WTFgenes specifications

Interface:
Web user interface
Programming languages:
C++, Javascript
Stability:
Stable
Restrictions to use:
None
Computer skills:
Basic
Maintained:
Yes

WTFgenes support

Documentation

Maintainer

  • Ian Holmes <>
  • Ian Holmes <>

Credits

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Publications

Institution(s)

Interprets experimentally-identified lists of genes. WTFgenes uses hypergeometric and model-based approaches. It permits to know what is the function of different genes thanks to Bayesian Term Enrichment Analysis (TEA). The tool can readily be extended to allow for datasets that are structured temporally, spatially, or by genomic region; to use domain-specific biological knowledge; or to incorporate additional lines of evidence such as quantitative data.

Funding source(s)

Supported by NHGRI grant HG004483; by Office of the Director R24-OD011883 and by the Director, Office of Science, Office of Basic Energy Sciences, of the US Department of Energy under Contract No. DE-AC02-05CH11231.

Link to literature

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