Whole-genome sequencing data analysis bioinformatics software tools

WGS analysis steps

Preprocessing & quality control

Data analysis

Annotation & interpretation

File, data & workflows

WGS analysis workflow

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WGS analysis workflow schema
Whole genome sequencing (WGS) is the next-generation sequencing technology for a rapid and low cost determining of the full genomic sequence of an organism. Deep sequencing of genomes is important not only to improve our knowledge in life sciences…

Whole-genome sequencing data analysis bioinformatics software tools

Most Recent Tools

PCGR
Desktop

PCGR Personal Cancer Genome Reporter

Generates a tiered report that will aid the interpretation of individual cancer…

Generates a tiered report that will aid the interpretation of individual cancer genomes in a clinical setting. PCGR is a stand¬alone, open¬source software package for somatic variant annotation…

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Cooler
Desktop

Cooler

Provides Python API to work with Hi-C data. Cooler is a support library for a…

Provides Python API to work with Hi-C data. Cooler is a support library for a sparse, compressed, binary persistent storage format for Hi-C contact matrices, called cool or COOL. The software…

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Scallop
Desktop

Scallop

Enables accurate identification of multi-exon transcripts and lowly expressed…

Enables accurate identification of multi-exon transcripts and lowly expressed transcripts. Scallop is an accurate reference-based transcript assembler. The software uses a novel algorithm to…

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Ketrew
Desktop

Ketrew

Provides an EDSL API to define complex and convoluted workflows…

Provides an EDSL API to define complex and convoluted workflows ((interdependent steps/programs using a lot of data, with many parameter variations, running on different hosts with various…

Most Popular Tools

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SAMtools
Desktop

SAMtools

A suite of programs for interacting with high-throughput sequencing data. It…

A suite of programs for interacting with high-throughput sequencing data. It can manipulate alignments in the SAM/BAM/CRAM formats : reading, writing, editing, indexing, viewing and converting…

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Bowtie
Desktop

Bowtie

An ultrafast, memory-efficient short read aligner. It aligns short DNA…

An ultrafast, memory-efficient short read aligner. It aligns short DNA sequences (reads) to the human genome at a rate of over 25 million 35-bp reads per hour. Bowtie indexes the genome with a…

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SNPdryad
Web

SNPdryad

A computational method that can predict deleterious effect of amino acid…

A computational method that can predict deleterious effect of amino acid substitutions occurred in human proteins. SNPdryad outperforms other leading algorithms in accurately predicting deleterious…

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HOMER
Desktop

HOMER Hypergeometric Optimization of Motif EnRichment

A suite of tools for Motif Discovery and next-gen sequencing analysis. HOMER…

A suite of tools for Motif Discovery and next-gen sequencing analysis. HOMER contains many useful tools for analyzing ChIP-Seq, GRO-Seq, RNA-Seq, DNase-Seq, Hi-C and numerous other types of…

Curators for WGS analysis

  • Catherine Breton's avatar image
    Catherine Breton
    Institut des Sciences de…

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