Whole-genome sequencing data analysis bioinformatics software tools

WGS analysis steps

Laboratory information and management systems | HTS

LIMS

33 tools

Utilities (next-generation sequencing)

Utilities

74 tools

WGS analysis workflow

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WGS analysis workflow schema
Since 2005, whole-genome sequencing platforms have become widely available, reducing the cost of DNA sequencing by four orders of magnitude relative to Sanger sequencing (DNA sequencing costs; Metzker, 2010; Mardis, 2011). NGS technologies are being…

Whole-genome sequencing data analysis bioinformatics software tools

Most Recent Tools

Desktop app
G T A T C G C T A Fasta File Splitter Fasta File Splitter

Fasta File Splitter

Reads a protein FASTA file and splits it apart into a number of sections. Fasta…

Reads a protein FASTA file and splits it apart into a number of sections. Fasta File Splitter is a console application to break apart a large protein FASTA file into a series of smaller FASTA files,…

Desktop app
G T A T C G C T A iGC iGC

iGC

Identifies differentially expressed genes driven by Copy Number Alterations…

Identifies differentially expressed genes driven by Copy Number Alterations (CNA) from samples with both gene expression and CNA data. iGC supports multiple input formats and users can define their…

Desktop app
G T A T C G C T A Best cycle genotyping… Deprecated Best cycle genotyping algorithm

BCGA Best cycle genotyping algorithm

Classifies samples according to the behavior of blanks (no DNA samples), which…

Classifies samples according to the behavior of blanks (no DNA samples), which cluster with heterozygous samples. BCGA is based on the assumptions that classification depends on the time (cycle) of…

Desktop app
G T A T C G C T A Melting curve Single… Melting curve Single nucleotide polymorphism Base…

McSNP Base calling Melting curve Single nucleotide polymorphism Base calling

Comprises a peak detection procedure and an ordinal regression model. McSNP is…

Comprises a peak detection procedure and an ordinal regression model. McSNP is a relatively cheap and handy genotyping technique as it is an extension of the reverse transcription-polymerase chain…

Most Popular Tools

Desktop app
G T A T C G C T A SAMtools SAMtools

SAMtools

A suite of programs for interacting with high-throughput sequencing data. It…

A suite of programs for interacting with high-throughput sequencing data. It can manipulate alignments in the SAM/BAM/CRAM formats : reading, writing, editing, indexing, viewing and converting…

Desktop app
G T A T C G C T A Bowtie Bowtie

Bowtie

An ultrafast, memory-efficient short read aligner. It aligns short DNA…

An ultrafast, memory-efficient short read aligner. It aligns short DNA sequences (reads) to the human genome at a rate of over 25 million 35-bp reads per hour. Bowtie indexes the genome with a…

Web app
G T A T C G C T A SNPdryad SNPdryad

SNPdryad

A computational method that can predict deleterious effect of amino acid…

A computational method that can predict deleterious effect of amino acid substitutions occurred in human proteins. SNPdryad outperforms other leading algorithms in accurately predicting deleterious…

Desktop app
G T A T C G C T A Hypergeometric… Hypergeometric Optimization of Motif EnRichment

HOMER Hypergeometric Optimization of Motif EnRichment

A suite of tools for Motif Discovery and next-gen sequencing analysis. HOMER…

A suite of tools for Motif Discovery and next-gen sequencing analysis. HOMER contains many useful tools for analyzing ChIP-Seq, GRO-Seq, RNA-Seq, DNase-Seq, Hi-C and numerous other types of…

Curators for WGS analysis

  • Catherine Breton's avatar image
    Catherine Breton
    Institut des Sciences de…

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