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Yeast 5 specifications


Unique identifier OMICS_02994
Name Yeast 5
Restrictions to use None
Maintained Yes


  • Plants and Fungi
    • Saccharomyces cerevisiae

Publication for Yeast 5

Yeast 5 citations


Growth coupled overproduction is feasible for almost all metabolites in five major production organisms

Nat Commun
PMCID: 5489714
PMID: 28639622
DOI: 10.1038/ncomms15956

[…] ith growth at the 10% minimal product yield level reduces to 43.4%, which is nevertheless still significant. The mean cut set size increases by approximately seven reaction knockouts. Analogously, in yeast 52.4%, in A. niger even 81.4% and in C. glutamicum 35.9% of the metabolites can still be coupled at the 10% minimal yield level when all organic outflows present in the respective models are ope […]


High protein paternal diet confers an advantage to sons in sperm competition

PMCID: 5326516
PMID: 28202685
DOI: 10.1098/rsbl.2016.0914

[…] s and ubiquitously in somatic cells for paternity assignment (focal males) or red fluorescent protein (RFP; females and competitor males) in sperm heads []. GFP larvae were reared on high- (HP; 200 g yeast : 50 g sugar) or low-protein (LP; 50 g yeast : 50 g sugar) diet known to yield 80–96% survival []. For each treatment, 10 vials were prepared upon eclosion, each with five CO2-collected males an […]


E Flux2 and SPOT: Validated Methods for Inferring Intracellular Metabolic Flux Distributions from Transcriptomic Data

PLoS One
PMCID: 4915706
PMID: 27327084
DOI: 10.1371/journal.pone.0157101

[…] lation: 0.2009) than our method (DC+SPOT) whose average correlation is 0.7960 and 0.8117 in E. coli and in yeast, respectively (). Unlike a prokaryote model such as iJO1366, a eukaryote model such as Yeast 5 is compartmentalized into organelles (e.g. mitochondria, peroxisomes, lysosomes, ER, and nucleus). As can be seen in , the set of measured intracellular fluxes that were used for validation in […]


Noncanonical registers and base pairs in human 5′ splice site selection

Nucleic Acids Res
PMCID: 4856993
PMID: 26969736
DOI: 10.1093/nar/gkw163

[…] of +4A in mammals (). We propose that the functional significance of this interaction might be different between yeast and mammals. +4U forms a weaker base pair with U1 nucleotide Ψ5 than +4A, and in yeast 5′ss such interaction facilitates the U1-off rate from the 5′ss, and thus its replacement by U6 during spliceosome assembly (), which is rate limiting in this species (). We disfavor the U1/U6 r […]


Melanocortin 3 Receptor Signaling in Midbrain Dopamine Neurons Increases the Motivation for Food Reward

PMCID: 4946052
PMID: 26852738
DOI: 10.1038/npp.2016.19

[…] 10 min) and further acetylated (10 min). Following acetylation, slices were preincubated with a prehybridization mix (50% deionized formamide, 5 × SSC, 5 × Denhardt's solution, 250 μg/ml tRNA baker's yeast, 500 μg/ml sonicated salmon sperm DNA final concentrations in MilliQ). Next, the sections were incubated overnight at 40 °C in 120 μl hybridization mix (Panomics) containing the probe sets (conc […]


Comparative Analysis of Yeast Metabolic Network Models Highlights Progress, Opportunities for Metabolic Reconstruction

PLoS Comput Biol
PMCID: 4643975
PMID: 26566239
DOI: 10.1371/journal.pcbi.1004530

[…] to enable FBA with COBRA ToolboxiMM904—downloaded from BIGG database []Yeast 4—downloaded from yeast.sf.netiAZ900—from [] supplemental infoiMM904bs—[] Yeast 5—downloaded from yeast.sf.netiTO977—provided by Markus Herrgard—differs from published version with addition of CoA sink to enable FBA with the COBRA Toolbox. Modifications include: setting obj […]


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Yeast 5 institution(s)
Department of Biological and Environmental Engineering, Cornell University, Ithaca, NY, USA

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