Offers assembly and gene annotation of Yersinia pestis, which is in the Enterobacteriaceae family. Yersiniae consist of 11 species that have been traditionally distinguished by DNA-DNA hybridisation and biochemical analyses. The database generates reference genomes for two of the human pathogenic Yersinia: Y. pestis and Y. enterocolitica. The genome of Y. pestis is punctuated with pseudogenes demonstrating that despite its high virulence Y. pestis is in the early stage of genome decay, eliminating genes no longer required outside it mammalian host.
McMaster Ancient DNA Centre, Department of Anthropology, McMaster University, Hamilton, ON, Canada; Institute for Archaeological Sciences, University of Tübingen, Tübingen, Germany; Biology Department, McMaster University, Hamilton, ON, Canada; Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany; Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, ON, Canada; Department of Anthropology, University of South Carolina, Columbia, SC, USA; Department of Biological Sciences, University of South Carolina, Columbia, SC, USA; Institute of Applied Genetics, University of North Texas Health Science Center, Fort Worth, TX, USA; Department of Anthropology and Population Research Institute, Pennsylvania State University, University Park, PA, USA; Department of Mathematics and Statistics, Hamilton, ON, Canada; Department of Anthropology, McMaster University, Hamilton, ON, Canada; Human Genetics Department, Medical Faculty, University of Tübingen, Tübingen, Germany