ZFN-Site statistics

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Citations per year

Number of citations per year for the bioinformatics software tool ZFN-Site

Tool usage distribution map

This map represents all the scientific publications referring to ZFN-Site per scientific context
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ZFN-Site specifications


Unique identifier OMICS_04718
Name ZFN-Site
Interface Web user interface
Restrictions to use None
Programming languages C, Perl
License GNU General Public License version 2.0
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Thomas J. Cradick

Publication for ZFN-Site

ZFN-Site citations


Multidimensional Genome wide Analyses Show Accurate FVIII Integration by ZFN in Primary Human Cells

PMCID: 4786920
PMID: 26689265
DOI: 10.1038/mt.2015.223

[…] The high-confidence somatic variants were analyzed further to generate the final list of candidate indels for experimental validation.Putative off-target sites in hg19 were identified in silico using ZFN-Site. The left and right ZFN half-sites were ATCCTGTCCCTA and ACCCCACAGTGG, respectively. The allowed spacing was 5 or 6 bp and the maximum number of mismatches per half-site was set to 2. There w […]


Zinc finger nucleases mediate specific and efficient excision of HIV 1 proviral DNA from infected and latently infected human T cells

Nucleic Acids Res
PMCID: 3763554
PMID: 23804764
DOI: 10.1093/nar/gkt571

[…] of ZFN specificity initially in the target site selection and ZFN design. The selected target site of ZFN-LTR was so carefully chosen, that even using the most stringent definitions available for the ZFN-Site online bioinformatics tool (), we did not find any homologous or similar sequence of the target site in the human genome. On the other hand, we obtained a commercially designed pair of ZFNs: […]

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ZFN-Site institution(s)
University of Iowa School of Medicine, Department of Internal Medicine, Iowa City, IA, USA

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