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Zinc finger nuclease design software tools | Genome engineering data analysis

Zinc-finger nucleases (ZFNs) are targetable DNA cleavage reagents that have been adopted as gene-targeting tools. ZFN-induced double-strand breaks are subject to cellular DNA repair processes that lead to both targeted mutagenesis and targeted gene replacement at remarkably high frequencies.

Source text:
(Carroll, 2011) Genome engineering with zinc-finger nucleases. Genetics.

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