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ZiFDB specifications


Unique identifier OMICS_04710
Name ZiFDB
Alternative name Zinc Finger Database
Restrictions to use None
Maintained No

Publication for Zinc Finger Database

ZiFDB citations


Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation

Nat Commun
PMCID: 5458116
PMID: 28537256
DOI: 10.1038/ncomms15336

[…] this end, five different target DNA sites overlapping with GANTC motifs were selected. Then, three domain C2H2 ZnF proteins binding to these sequences were identified by Zinc Finger Targeter from the Zinc Finger Database and ZnF arrays were tested for DNA binding in E. coli using a bacterial two-hybrid system as described (Addgene Kit # 1000000010). The sensitivity of ZnF binding to methylated tar […]


Integrating gene synthesis and microfluidic protein analysis for rapid protein engineering

Nucleic Acids Res
PMCID: 4838357
PMID: 26704969
DOI: 10.1093/nar/gkv1497

[…] All ZF modules used in this study were either taken from the Zinc Finger Consortium's online Zinc Finger Database (), or from references () and (), which contain natural and designed single ZF modules or concatenated, multi-finger arrays. Other ZF modules were designed using online DNA bindin […]


ZFNGenome: A comprehensive resource for locating zinc finger nuclease target sites in model organisms

BMC Genomics
PMCID: 3042413
PMID: 21276248
DOI: 10.1186/1471-2164-12-83

[…] nger Nuclease Site track, clicking on (AGCAGCGTCNNNNNNNGAAGGTGTG) opens a page containing more information about the site, as illustrated in Figure . The "Note" sections on this page provide links to ZiFDB [], a repository for zinc finger arrays that have been experimentally validated, and ZiFiT [], a tool for identifying potential ZFP and ZFN target sites. A hyperlink to NCBI BLAST [] can be used […]


Zinc Finger Database (ZiFDB): a repository for information on C2H2 zinc fingers and engineered zinc finger arrays

Nucleic Acids Res
PMCID: 2686427
PMID: 18812396
DOI: 10.1093/nar/gkn606

[…] labor-intensive and difficult to perform than modular assembly.Because many scientists are interested in generating zinc-finger proteins for gene regulation and genome modification, we implemented a Zinc Finger Database (ZiFDB)—an archive of information about zinc fingers and engineered ZFAs. The database is one of several, integrated resources provided by the Zinc Finger Consortium (http://www.z […]


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ZiFDB institution(s)
Department of Genetics, University of Minnesota, Minneapolis, MN, USA

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