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|Alternative name||Zebrafish Mutation Project|
|Restrictions to use||None|
- Danio rerio
Publication for Zebrafish Mutation Project
Genes Regulated by Vitamin D in Bone Cells Are Positively Selected in East Asians
[…] d database that includes ~2,700 genes causing human diseases culled from OMIM and the Human Gene Mutation Database Professional. In addition, phenotypes for knock-out zebrafish were obtained from the Zebrafish Mutation Project (http://www.sanger.ac.uk/Projects/D_rerio/zmp/) and those for the mouse from the International Knockout Mouse Consortium and International Mouse Phenotyping Consortium (http […]
Computational evaluation of exome sequence data using human and model organism phenotypes improves diagnostic efficiency
[…] the mutant model organism databases accumulate more data and as improvements are made to the phenotype comparison algorithm. Initiatives such as the International Mouse Phenotyping Consortium and the Zebrafish Mutation Project will greatly expand the available knowledge about gene–phenotype relationships. Also, incorporation of additional species' phenotype data into Exomiser will improve its perf […]
The emerging use of zebrafish to model metabolic disease
[…] d with the chemical ethylnitrosourea (ENU) can be used. Gene-specific mutations can be identified by carrying out loci-specific PCR or, more recently, by whole-exome sequencing, as exemplified by the Zebrafish Mutation Project () (). A further advance has been the use of transcription activator-like effector nucleases (TALENs) () and the CRISPR-Cas system () to create targeted mutations. Both of t […]
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