Zyggregator statistics

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Zyggregator specifications

Information


Unique identifier OMICS_03864
Name Zyggregator
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained No

Publication for Zyggregator

Zyggregator in publications

 (41)
PMCID: 5900942
PMID: 29315487
DOI: 10.1002/bit.26543

[…] successfully from molecule to market (jain et al., ; tiller & tessier, ; van der kant et al., ). in silico analyses, such as tango (fernandez‐escamilla, rousseau, schymkowitz, & serrano, ), zyggregator (tartaglia & vendruscolo, ), waltz (oliveberg, ), aggrescan (conchillo‐solé et al., ), and pasta (trovato, seno, & tosatto, ) can be used to predict the presence […]

PMCID: 5684091
PMID: 29132128
DOI: 10.1016/j.redox.2017.10.022

[…] regulator bcl-xl are predicted to be highly destabilized, with δδg values of 4.57 and 6.38 kcal/mol, respectively.fig. 7fig. 7, the sequence-based aggregation prediction algorithms aggrescan and zyggregator were used to assess if asp, and by analogy cyso3h, might act creating new or stronger “hot spots” that favours the aggregation in the oxidized ff domain. no significant changes […]

PMCID: 5608858
PMID: 28935930
DOI: 10.1038/s41598-017-09714-z

[…] in all the above described proteins (figs  to )., the predicted soft amyloid cores for these proteins are shown in table . remarkably, well-validated aggregation predictors like aggrescan, tango and zyggregator failed to classify these stretches as aggregation-prone, the exception being the phc1 core, which was identified by tango (table ). the underlying reason explaining why these amyloid […]

PMCID: 5528828
PMID: 28746363
DOI: 10.1371/journal.pone.0181799

[…] can be a precious tool to study a multitude of sequences. we compared our mas ssnmr results with the predictions from three web tools (). in our benchmark, we included aggrescan [], tango [] and zyggregator []. of the four β-strands identified by mas ssnmr, all algorithms identified the two longer c-terminal β-strands between residues 70 and 90. our first n-terminal β-strand […]

PMCID: 5206856
PMID: 28096892
DOI: 10.1155/2016/6247867

[…] tools to approximate the 3-point mutations that are both stable and least amyloidogenic, which would result in slower amyloid formation and slower disease progression. in particular, we use zyggregator [], tango [], and pasta [] to predict the aggregation propensities of the top ranking stable 3-point mutations. the top 3 mutations with best stability and lowest amyloidogenicity […]


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Zyggregator institution(s)
Department of Chemistry, University of Cambridge, Cambridge, UK

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